Tyrosine
Tyrosine is a conditionally essential amino acid that serves as a precursor for catecholamine neurotransmitters (dopamine, norepinephrine, epinephrine), thyroid hormones, and melanin pigment synthesis. It has been investigated for cognitive enhancement, stress resilience, and treatment of conditions involving catecholamine depletion such as phenylketonuria and early Parkinson's disease and Alzheimer's disease. As a substrate for melanin production, it is also relevant in melanoma biology and skin pigmentation disorders.
Peso Molecular
181,1900 g/mol
LogP
-2,30
TPSA
83,60 Ų
Regra dos 5 de Lipinski
Aprovado
Áreas Terapêuticas
Mecanismo de Ação
Stimulates melanocyte proliferation and melanin synthesis, increasing photoprotective pigmentation in the skin.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Stimulates melanocyte proliferation and melanin synthesis, increasing photoprotective pigmentation in the skin.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
N[C@@H](Cc1ccc(O)cc1)C(=O)O
InChI
InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
Molecular Formula
C9H11NO3
HBD / HBA
3 / 4
Ligações Rotacionáveis
3
Átomos Pesados
13
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
Tyrosine is a conditionally essential amino acid that serves as a precursor for catecholamine neurotransmitters (dopamine, norepinephrine, epinephrine), thyroid hormones, and melanin pigment synthesis. It has been investigated for cognitive enhancement, stress resilience, and treatment of conditions involving catecholamine depletion such as phenylketonuria and early Parkinson's disease and Alzheimer's disease. As a substrate for melanin production, it is also relevant in melanoma biology and skin pigmentation disorders.
Stimulates melanocyte proliferation and melanin synthesis, increasing photoprotective pigmentation in the skin.
Yes, Tyrosine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL925. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 6057. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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