Vilazodone

CHEMBL439849 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

441.5 g/mol

LogP

4.0

Phase

4

This antidepressant is used to treat major depressive disorder and works through a dual mechanism: it blocks serotonin reuptake (like SSRIs) and partially activates serotonin receptors (5-HT1A), which may improve its effectiveness and tolerability. It is taken once daily with food, as food significantly increases its absorption. Nausea and diarrhea are the most common side effects, particularly when starting treatment.

Peso Molecular

441,5000 g/mol

LogP

4,00

TPSA

102,00 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Bipolar Disorder Generalized Anxiety Disorder Major Depressive Disorder

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc5oc(C(N)=O)cc5c4)CC3)c2c1

InChI

InChI=1S/C26H27N5O2/c27-16-18-4-6-23-22(13-18)19(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-5-7-24-20(14-21)15-25(33-24)26(28)32/h4-7,13-15,17,29H,1-3,8-12H2,(H2,28,32)

Molecular Formula

C26H27N5O2

HBD / HBA

2 / 5

Ligações Rotacionáveis

7

Átomos Pesados

33

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

This antidepressant is used to treat major depressive disorder and works through a dual mechanism: it blocks serotonin reuptake (like SSRIs) and partially activates serotonin receptors (5-HT1A), which may improve its effectiveness and tolerability. It is taken once daily with food, as food significantly increases its absorption. Nausea and diarrhea are the most common side effects, particularly when starting treatment.

Yes, Vilazodone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL439849. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6918314. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

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Estrutura

Dados Rápidos

Fórmula: C26H27N5O2
Sinônimos: 1

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.