Pharmacogenomics (PGx)
PGxThe study of how genetic variation affects drug response. Enables precision medicine by predicting efficacy, dosing requirements, and adverse reaction risk based on patient genotype.
Exemplos
- CYP2D6 for codeine/tamoxifen
- HLA-B*5701 for abacavir
- CYP2C19 for clopidogrel
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The study of how genetic variation affects drug response. Enables precision medicine by predicting efficacy, dosing requirements, and adverse reaction risk based on patient genotype.