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Rufinamide

CHEMBL1201754 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
238.2 g/mol
LogP
0.7
Phase
4

An anticonvulsant used primarily as adjunctive therapy for seizures associated with Lennox-Gastaut syndrome, a severe childhood epilepsy disorder. It works by modulating sodium channel activity in neurons to reduce the frequency and severity of seizures.

Молекулярная масса

238,1900 g/mol

LogP

0,70

TPSA

73,80 Ų

Правило пяти Липинского

Соответствует

Терапевтические области

Pain Management Epilepsy Generalized Anxiety Disorder Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
NC(=O)c1cn(Cc2c(F)cccc2F)nn1

                

                

                
                

                    
InChI

                    
InChI=1S/C10H8F2N4O/c11-7-2-1-3-8(12)6(7)4-16-5-9(10(13)17)14-15-16/h1-3,5H,4H2,(H2,13,17)

                

                

                

                    
                    

                        
Molecular Formula

                        
C10H8F2N4O

                    

                    
                    

                        
HBD / HBA

                        
1 / 5

                    

                    
                    

                        
Вращаемые Связи

                        
3

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
17

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
An anticonvulsant used primarily as adjunctive therapy for seizures associated with Lennox-Gastaut syndrome, a severe childhood epilepsy disorder. It works by modulating sodium channel activity in neurons to reduce the frequency and severity of seizures.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Rufinamide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1201754.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 129228.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.