Maximum Plasma Concentration (Cmax)

Cmax
Pharmacokinetics

The highest plasma drug concentration achieved after administration. Reflects the rate and extent of absorption for oral drugs. Key parameter for determining peak-related toxicity and efficacy.

Примеры

  • Higher Cmax with IV vs oral
  • Food effects on Cmax
  • Dose-proportional Cmax in linear PK

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The highest plasma drug concentration achieved after administration. Reflects the rate and extent of absorption for oral drugs. Key parameter for determining peak-related toxicity and efficacy.