HRH1 (Histamine H1 Receptor)
HRH1
G-protein coupled receptor (Gq) mediating allergic and inflammatory responses.
Функция
H1 antagonists (antihistamines) block histamine-induced vasodilation, itching, and bronchoconstriction.
Препараты, действующие на данную мишень
| Препарат | Действие | Первичный |
|---|---|---|
| Trazodone | Antagonist | Да |
| Cetirizine | Antagonist | Да |
| Loratadine | Antagonist | Да |
| Diphenhydramine | Antagonist | Да |
| Memantine | Antagonist | — |
| Quetiapine | Antagonist | — |
| Ondansetron | Antagonist | — |
| Escitalopram | Antagonist | — |
Related Targets
OPRM1 (Mu-Opioid Receptor)
OPRM1
PDCD1 (Programmed Cell Death Protein 1)
PDCD1
SIGMAR1 (Sigma-1 Receptor)
SIGMAR1
AGTR1 (Angiotensin II Type 1 Receptor)
AGTR1
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4)
CTLA4
ADRB1 (Beta-1 Adrenergic Receptor)
ADRB1
ADRB2 (Beta-2 Adrenergic Receptor)
ADRB2
DRD2 (Dopamine D2 Receptor)
DRD2