Captopril

CHEMBL1560 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

1.9 hours

Bioavailability

—

Protein Binding

—

Molecular Weight

217.3 g/mol

LogP

0.3

Phase

4

The first orally active ACE inhibitor, used to treat hypertension, heart failure, and to protect kidney function in diabetic nephropathy. By blocking the angiotensin-converting enzyme, it prevents the formation of angiotensin II, leading to blood vessel relaxation and reduced aldosterone secretion. A dry persistent cough is a characteristic and common side effect.

น้ำหนักโมเลกุล

217.2850 g/mol

LogP

0.30

TPSA

58.60 Å²

Lipinski RO5

ผ่าน

ด้านการรักษา

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Chronic Kidney Disease Stroke Obesity Type 2 Diabetes Hypertension Breast Cancer Heart Failure Atrial Fibrillation Prostate Cancer Colorectal Cancer Leukemia

หมวดหมู่ยา

C — C - Cardiovascular System

กลไกการออกฤทธิ์

First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Pharmacokinetics (PK)

Half-Life 1.9 hours

Pharmacodynamics (PD)

กลไก

First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

โครงสร้าง 2 มิติ

SVG PNG

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SMILES

C[C@H](CS)C(=O)N1CCC[C@H]1C(=O)O

InChI

InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1

Molecular Formula

C9H15NO3S

HBD / HBA

2 / 4

พันธะที่หมุนได้

3

อะตอมหนัก

14

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

The first orally active ACE inhibitor, used to treat hypertension, heart failure, and to protect kidney function in diabetic nephropathy. By blocking the angiotensin-converting enzyme, it prevents the formation of angiotensin II, leading to blood vessel relaxation and reduced aldosterone secretion. A dry persistent cough is a characteristic and common side effect.

First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

Key pharmacokinetic parameters for Captopril: Half-life: 1.9 hours.

Yes, Captopril is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

Related Drugs

Same Drug Class

Atorvastatin Small molecule Amlodipine Small molecule Lisinopril Small molecule Metoprolol Small molecule

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1560. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 44093. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Captopril บน PillFYI

โครงสร้าง

ข้อมูลด่วน

Class: C - Cardiovascular System
สูตร: C9H15NO3S

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.

Captopril

ด้านการรักษา

หมวดหมู่ยา

กลไกการออกฤทธิ์

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

Cite this structure

Embed this structure

No targets recorded

No interactions recorded

No side effects recorded

คำถามที่พบบ่อย

Related Drugs

Same Drug Class

References & Data Sources

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