Enalapril

CHEMBL578 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

11 hours

Bioavailability

—

Protein Binding

—

Molecular Weight

376.4 g/mol

LogP

-0.1

Phase

4

This medication relaxes blood vessels by blocking an enzyme that produces a hormone called angiotensin II, making it easier for the heart to pump blood. It is widely used to treat high blood pressure and heart failure.

น้ำหนักโมเลกุล

376.4470 g/mol

LogP

-0.10

TPSA

95.90 Å²

Lipinski RO5

ผ่าน

ด้านการรักษา

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Cardiovascular Disease Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Melanoma Systemic Lupus Erythematosus Chronic Kidney Disease Stroke Hyperlipidemia Obesity Lymphoma Type 2 Diabetes Hypertension Breast Cancer Chronic Pain Heart Failure Atrial Fibrillation Prostate Cancer Colorectal Cancer Leukemia

หมวดหมู่ยา

C — C - Cardiovascular System

กลไกการออกฤทธิ์

Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

Pharmacokinetics (PK)

Half-Life 11 hours

Pharmacodynamics (PD)

กลไก

Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

โครงสร้าง 2 มิติ

SVG PNG

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SMILES

CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O

InChI

InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1

Molecular Formula

C20H28N2O5

HBD / HBA

2 / 6

พันธะที่หมุนได้

10

อะตอมหนัก

27

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

This medication relaxes blood vessels by blocking an enzyme that produces a hormone called angiotensin II, making it easier for the heart to pump blood. It is widely used to treat high blood pressure and heart failure.

Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.

Key pharmacokinetic parameters for Enalapril: Half-life: 11 hours.

Yes, Enalapril is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

Related Drugs

Same Drug Class

Atorvastatin Small molecule Amlodipine Small molecule Lisinopril Small molecule Metoprolol Small molecule

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL578. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5388962. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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โครงสร้าง

ข้อมูลด่วน

Class: C - Cardiovascular System
สูตร: C20H28N2O5
คำพ้องความหมาย: 6

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.

Enalapril

ด้านการรักษา

หมวดหมู่ยา

กลไกการออกฤทธิ์

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

Cite this structure

Embed this structure

No targets recorded

No interactions recorded

No side effects recorded

คำถามที่พบบ่อย

Related Drugs

Same Drug Class

References & Data Sources

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