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Hexachlorophene

CHEMBL496 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
406.9 g/mol
LogP
7.5
Phase
4

A topical antiseptic used in surgical scrubs and skin cleansing products that kills bacteria by disrupting their cell membranes. Due to concerns about neurotoxicity, particularly in infants where it can be absorbed through the skin and cause brain damage, its use has been significantly restricted. In adults, it remains used in specific clinical antiseptic preparations under controlled conditions.

น้ำหนักโมเลกุล

406.9000 g/mol

LogP

7.50

TPSA

40.50 Ų

Lipinski RO5

ผ่าน

กลไกการออกฤทธิ์

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

กลไก

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

โครงสร้าง 2 มิติ

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Oc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl

                

                

                
                

                    
InChI

                    
InChI=1S/C13H6Cl6O2/c14-6-2-8(16)12(20)4(10(6)18)1-5-11(19)7(15)3-9(17)13(5)21/h2-3,20-21H,1H2

                

                

                

                    
                    

                        
Molecular Formula

                        
C13H6Cl6O2

                    

                    
                    

                        
HBD / HBA

                        
2 / 2

                    

                    
                    

                        
พันธะที่หมุนได้

                        
2

                    

                    
                    
                    

                        
อะตอมหนัก

                        
21

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
คำถามที่พบบ่อย

                

                    
                    

                        
                        

                            
A topical antiseptic used in surgical scrubs and skin cleansing products that kills bacteria by disrupting their cell membranes. Due to concerns about neurotoxicity, particularly in infants where it can be absorbed through the skin and cause brain damage, its use has been significantly restricted. In adults, it remains used in specific clinical antiseptic preparations under controlled conditions.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Hexachlorophene is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL496.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3598.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
ข้อจำกัดความรับผิดชอบทางการแพทย์

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.