Hexachlorophene
A topical antiseptic used in surgical scrubs and skin cleansing products that kills bacteria by disrupting their cell membranes. Due to concerns about neurotoxicity, particularly in infants where it can be absorbed through the skin and cause brain damage, its use has been significantly restricted. In adults, it remains used in specific clinical antiseptic preparations under controlled conditions.
Peso Molecular
406,9000 g/mol
LogP
7,50
TPSA
40,50 Ų
Regra dos 5 de Lipinski
Aprovado
Mecanismo de Ação
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Estrutura 2D
Cite this structure
Embed this structure
SMILES
Oc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl
InChI
InChI=1S/C13H6Cl6O2/c14-6-2-8(16)12(20)4(10(6)18)1-5-11(19)7(15)3-9(17)13(5)21/h2-3,20-21H,1H2
Molecular Formula
C13H6Cl6O2
HBD / HBA
2 / 2
Ligações Rotacionáveis
2
Átomos Pesados
21
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
A topical antiseptic used in surgical scrubs and skin cleansing products that kills bacteria by disrupting their cell membranes. Due to concerns about neurotoxicity, particularly in infants where it can be absorbed through the skin and cause brain damage, its use has been significantly restricted. In adults, it remains used in specific clinical antiseptic preparations under controlled conditions.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Hexachlorophene is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL496. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3598. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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