Hexachlorophene

CHEMBL496 Phase 4 Đã phê duyệt Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
406.9 g/mol
LogP
7.5
Phase
4

A topical antiseptic used in surgical scrubs and skin cleansing products that kills bacteria by disrupting their cell membranes. Due to concerns about neurotoxicity, particularly in infants where it can be absorbed through the skin and cause brain damage, its use has been significantly restricted. In adults, it remains used in specific clinical antiseptic preparations under controlled conditions.

Khối lượng phân tử

406,9000 g/mol

LogP

7,50

TPSA

40,50 Ų

Lipinski RO5

Đạt

Cơ chế tác dụng

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Cấu trúc 2D

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SMILES

Oc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl

InChI

InChI=1S/C13H6Cl6O2/c14-6-2-8(16)12(20)4(10(6)18)1-5-11(19)7(15)3-9(17)13(5)21/h2-3,20-21H,1H2

Molecular Formula

C13H6Cl6O2

HBD / HBA

2 / 2

Liên kết có thể quay

2

Nguyên tử nặng

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Câu hỏi thường gặp

A topical antiseptic used in surgical scrubs and skin cleansing products that kills bacteria by disrupting their cell membranes. Due to concerns about neurotoxicity, particularly in infants where it can be absorbed through the skin and cause brain damage, its use has been significantly restricted. In adults, it remains used in specific clinical antiseptic preparations under controlled conditions.

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Yes, Hexachlorophene is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL496. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 3598. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Tuyên bố miễn trách y tế

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.