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Sulfamerazine

CHEMBL438 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
264.3 g/mol
LogP
0.1
Phase
4

Sulfamerazine is an intermediate-acting sulfonamide antibiotic used in combination with other sulfonamides (trisulfapyrimidines) for the treatment of urinary tract infections, nocardiosis, and other susceptible bacterial infections. Combination sulfonamide therapy reduces the risk of crystalluria by lowering the individual concentration of each sulfonamide while maintaining antibacterial activity. Like all sulfonamides, it inhibits dihydropteroate synthase in susceptible bacteria.

น้ำหนักโมเลกุล

264.3100 g/mol

LogP

0.10

TPSA

106.00 Ų

Lipinski RO5

ผ่าน

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1

                

                

                
                

                    
InChI

                    
InChI=1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)

                

                

                

                    
                    

                        
Molecular Formula

                        
C11H12N4O2S

                    

                    
                    

                        
HBD / HBA

                        
2 / 6

                    

                    
                    

                        
พันธะที่หมุนได้

                        
3

                    

                    
                    
                    

                        
อะตอมหนัก

                        
18

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
คำถามที่พบบ่อย

                

                    
                    

                        
                        

                            
Sulfamerazine is an intermediate-acting sulfonamide antibiotic used in combination with other sulfonamides (trisulfapyrimidines) for the treatment of urinary tract infections, nocardiosis, and other susceptible bacterial infections. Combination sulfonamide therapy reduces the risk of crystalluria by lowering the individual concentration of each sulfonamide while maintaining antibacterial activity. Like all sulfonamides, it inhibits dihydropteroate synthase in susceptible bacteria.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Sulfamerazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL438.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5325.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
ข้อจำกัดความรับผิดชอบทางการแพทย์

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.