Sulfamethoxazole
Combined with trimethoprim (as co-trimoxazole), this sulfonamide antibiotic blocks two sequential steps in bacterial folate synthesis, making the combination highly effective against a wide range of bacterial and protozoal infections. It is a first-line treatment for urinary tract infections, Pneumocystis pneumonia in immunocompromised patients, and several other conditions.
น้ำหนักโมเลกุล
253.2800 g/mol
LogP
0.90
TPSA
107.00 Ų
Lipinski RO5
ผ่าน
ด้านการรักษา
Pharmacokinetics (PK)
Pharmacodynamics (PD)
โครงสร้าง 2 มิติ
Cite this structure
Embed this structure
SMILES
Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
InChI
InChI=1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
Molecular Formula
C10H11N3O3S
HBD / HBA
2 / 6
พันธะที่หมุนได้
3
อะตอมหนัก
17
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
คำถามที่พบบ่อย
Combined with trimethoprim (as co-trimoxazole), this sulfonamide antibiotic blocks two sequential steps in bacterial folate synthesis, making the combination highly effective against a wide range of bacterial and protozoal infections. It is a first-line treatment for urinary tract infections, Pneumocystis pneumonia in immunocompromised patients, and several other conditions.
Yes, Sulfamethoxazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL443. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5329. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
ข้อจำกัดความรับผิดชอบทางการแพทย์
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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