Sulfisoxazole

CHEMBL453 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
267.3 g/mol
LogP
1.0
Phase
4

Sulfisoxazole is a short-acting sulfonamide antibiotic with high urinary and tissue concentrations, used for the treatment of urinary tract infections, acute otitis media (in combination with erythromycin), and nocardiosis caused by susceptible organisms. It achieves higher free drug concentrations in urine than many sulfonamides due to lower plasma protein binding, making it particularly effective for urinary infections. Combination with erythromycin was previously used for penicillin-allergic patients with acute otitis media.

น้ำหนักโมเลกุล

267.3100 g/mol

LogP

1.00

TPSA

107.00 Ų

Lipinski RO5

ผ่าน

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

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SMILES

Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C

InChI

InChI=1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3

Molecular Formula

C11H13N3O3S

HBD / HBA

2 / 6

พันธะที่หมุนได้

3

อะตอมหนัก

18

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

Sulfisoxazole is a short-acting sulfonamide antibiotic with high urinary and tissue concentrations, used for the treatment of urinary tract infections, acute otitis media (in combination with erythromycin), and nocardiosis caused by susceptible organisms. It achieves higher free drug concentrations in urine than many sulfonamides due to lower plasma protein binding, making it particularly effective for urinary infections. Combination with erythromycin was previously used for penicillin-allergic patients with acute otitis media.

Yes, Sulfisoxazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL453. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5344. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.