Tilbroquinol

CHEMBL1788385 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

238.1 g/mol

LogP

3.1

Phase

4

Tilbroquinol is a halogenated hydroxyquinoline derivative with amebicidal and anti-infective activity, used in combination with tiliquinol (as Intetrix) for the treatment of intestinal amebiasis and amoebic dysentery. It acts within the intestinal lumen to directly kill Entamoeba histolytica trophozoites through disruption of cellular metabolism and membrane integrity. Its luminal activity makes it effective for intestinal but not extraintestinal amebiasis.

น้ำหนักโมเลกุล

238.0800 g/mol

LogP

3.10

TPSA

33.10 Å²

Lipinski RO5

ผ่าน

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

SVG PNG

Cite this structure

Embed this structure

SMILES

Cc1cc(Br)c(O)c2ncccc12

InChI

InChI=1S/C10H8BrNO/c1-6-5-8(11)10(13)9-7(6)3-2-4-12-9/h2-5,13H,1H3

Molecular Formula

C10H8BrNO

HBD / HBA

1 / 2

พันธะที่หมุนได้

0

อะตอมหนัก

13

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

Tilbroquinol is a halogenated hydroxyquinoline derivative with amebicidal and anti-infective activity, used in combination with tiliquinol (as Intetrix) for the treatment of intestinal amebiasis and amoebic dysentery. It acts within the intestinal lumen to directly kill Entamoeba histolytica trophozoites through disruption of cellular metabolism and membrane integrity. Its luminal activity makes it effective for intestinal but not extraintestinal amebiasis.

Yes, Tilbroquinol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1788385. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 65592. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

กำลังมองหาข้อมูลที่เข้าใจง่ายสำหรับผู้ป่วยอยู่ใช่ไหม?

Tilbroquinol บน PillFYI

โครงสร้าง

ข้อมูลด่วน

สูตร: C10H8BrNO

ลิงก์ภายนอก

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

ข้อจำกัดความรับผิดชอบทางการแพทย์

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.