Tilbroquinol

CHEMBL1788385 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

238.1 g/mol

LogP

3.1

Phase

4

Tilbroquinol is a halogenated hydroxyquinoline derivative with amebicidal and anti-infective activity, used in combination with tiliquinol (as Intetrix) for the treatment of intestinal amebiasis and amoebic dysentery. It acts within the intestinal lumen to directly kill Entamoeba histolytica trophozoites through disruption of cellular metabolism and membrane integrity. Its luminal activity makes it effective for intestinal but not extraintestinal amebiasis.

分子量

238.0800 g/mol

LogP

3.10

TPSA

33.10 Å²

Lipinski 五规则

符合

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

Cite this structure

Embed this structure

SMILES

Cc1cc(Br)c(O)c2ncccc12

InChI

InChI=1S/C10H8BrNO/c1-6-5-8(11)10(13)9-7(6)3-2-4-12-9/h2-5,13H,1H3

Molecular Formula

C10H8BrNO

HBD / HBA

1 / 2

可旋转键数

0

重原子数

13

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

Tilbroquinol is a halogenated hydroxyquinoline derivative with amebicidal and anti-infective activity, used in combination with tiliquinol (as Intetrix) for the treatment of intestinal amebiasis and amoebic dysentery. It acts within the intestinal lumen to directly kill Entamoeba histolytica trophozoites through disruption of cellular metabolism and membrane integrity. Its luminal activity makes it effective for intestinal but not extraintestinal amebiasis.

Yes, Tilbroquinol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1788385. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 65592. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

正在寻找患者友好型信息？

Tilbroquinol 在 PillFYI 上

结构

快速数据

分子式: C10H8BrNO

外部链接

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.