Vinorelbine

CHEMBL553025 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

778.9 g/mol

LogP

3.6

Phase

4

This semi-synthetic vinca alkaloid chemotherapy is used to treat non-small cell lung cancer and breast cancer, either alone or in combination with other chemotherapy agents. Like other vinca alkaloids, it works by blocking cell division by preventing the formation of the mitotic spindle in cancer cells. It can be given intravenously or as an oral capsule, and peripheral neuropathy and bone marrow suppression are the main side effects.

น้ำหนักโมเลกุล

778.9000 g/mol

LogP

3.60

TPSA

134.00 Å²

Lipinski RO5

ไม่ผ่าน

ด้านการรักษา

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Endometriosis Benign Prostatic Hyperplasia Glaucoma Cardiovascular Disease Age-Related Macular Degeneration Neurology Psychiatry Endocrinology Respiratory Disease Dermatology Hematology Pain Management Ophthalmology Non-Small Cell Lung Cancer Rheumatoid Arthritis Osteoporosis Asthma Chronic Obstructive Pulmonary Disease Immunology Alzheimer's Disease Parkinson's Disease Epilepsy Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Infectious Disease Melanoma Hepatology Oncology Nephrology Gastroesophageal Reflux Disease Inflammatory Bowel Disease Psoriasis Obstetrics & Gynecology Anesthesiology Systemic Lupus Erythematosus Multiple Sclerosis Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Urology Stroke Deep Vein Thrombosis / Pulmonary Embolism Hyperlipidemia Obesity Lymphoma Gastroenterology Rheumatology Transplant Medicine Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer Atopic Dermatitis Gout Chronic Pain Malaria HIV/AIDS Hepatitis C Tuberculosis Heart Failure Atrial Fibrillation Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

SVG PNG

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SMILES

CCC1=C[C@@H]2CN(C1)Cc1c([nH]c3ccccc13)[C@@](C(=O)OC)(c1cc3c(cc1OC)N(C)[C@H]1[C@@](O)(C(=O)OC)[C@H](OC(C)=O)[C@]4(CC)C=CCN5CC[C@]31[C@@H]54)C2

InChI

InChI=1S/C45H54N4O8/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3/t28-,37-,38+,39+,42+,43+,44-,45-/m0/s1

Molecular Formula

C45H54N4O8

HBD / HBA

2 / 11

พันธะที่หมุนได้

10

อะตอมหนัก

57

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

This semi-synthetic vinca alkaloid chemotherapy is used to treat non-small cell lung cancer and breast cancer, either alone or in combination with other chemotherapy agents. Like other vinca alkaloids, it works by blocking cell division by preventing the formation of the mitotic spindle in cancer cells. It can be given intravenously or as an oral capsule, and peripheral neuropathy and bone marrow suppression are the main side effects.

Yes, Vinorelbine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL553025. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5311497. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Vinorelbine บน PillFYI

โครงสร้าง

ข้อมูลด่วน

สูตร: C45H54N4O8

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.