Guanfacine Hydrochloride

CHEMBL1200494 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

282.5 g/mol

LogP

—

Phase

4

A hydrochloride salt form of guanfacine, an alpha-2 agonist used in the treatment of ADHD and also studied for its cognitive-enhancing and antihypertensive properties. The extended-release hydrochloride formulation allows once-daily dosing for ADHD management. It is a non-stimulant option suitable for patients who cannot tolerate or respond inadequately to stimulant medications.

Moleküler Ağırlık

282,5000 g/mol

TPSA

81,50 Å²

Terapötik Alanlar

Pain Management Asthma Schizophrenia Generalized Anxiety Disorder Insomnia Stroke Obesity Hypertension Major Depressive Disorder Chronic Pain Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

Cite this structure

Embed this structure

SMILES

Cl.N=C(N)NC(=O)Cc1c(Cl)cccc1Cl

InChI

InChI=1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H

Molecular Formula

C9H10Cl3N3O

HBD / HBA

3 / 1

Döndürülebilir Bağlar

2

Ağır Atomlar

16

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

A hydrochloride salt form of guanfacine, an alpha-2 agonist used in the treatment of ADHD and also studied for its cognitive-enhancing and antihypertensive properties. The extended-release hydrochloride formulation allows once-daily dosing for ADHD management. It is a non-stimulant option suitable for patients who cannot tolerate or respond inadequately to stimulant medications.

Yes, Guanfacine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200494. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 71401. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

Hasta dostu bilgi mi arıyorsunuz?

Guanfacine Hydrochloride PillFYI'da

Yapı

Hızlı Veriler

Formül: C9H10Cl3N3O
Eş Anlamlılar: 2

Dış Bağlantılar

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Tıbbi Sorumluluk Reddi

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.