Mephentermine
This sympathomimetic amine is used in anesthesia to treat low blood pressure (hypotension) by stimulating the release of norepinephrine and directly activating adrenergic receptors to constrict blood vessels and increase cardiac output. It is particularly useful for managing the blood pressure drops that can occur during spinal or general anesthesia.
Moleküler Ağırlık
163,2600 g/mol
LogP
2,40
TPSA
12,00 Ų
Lipinski RO5
Geçer
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Yapı
Cite this structure
Embed this structure
SMILES
CNC(C)(C)Cc1ccccc1
InChI
InChI=1S/C11H17N/c1-11(2,12-3)9-10-7-5-4-6-8-10/h4-8,12H,9H2,1-3H3
Molecular Formula
C11H17N
HBD / HBA
1 / 1
Döndürülebilir Bağlar
3
Ağır Atomlar
12
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
This sympathomimetic amine is used in anesthesia to treat low blood pressure (hypotension) by stimulating the release of norepinephrine and directly activating adrenergic receptors to constrict blood vessels and increase cardiac output. It is particularly useful for managing the blood pressure drops that can occur during spinal or general anesthesia.
Yes, Mephentermine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201234. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3677. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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