Sulfaphenazole

CHEMBL1109 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

314.4 g/mol

LogP

1.5

Phase

4

Sulfaphenazole is a sulfonamide antibacterial and potent inhibitor of cytochrome P450 2C9 (CYP2C9), used primarily as a research tool to characterize CYP2C9-mediated drug metabolism, and historically as an antibacterial agent for urinary tract infections. Its CYP2C9 inhibition causes clinically significant interactions with drugs metabolized by this enzyme including warfarin, tolbutamide, and phenytoin. The antibacterial mechanism involves inhibition of dihydropteroate synthase.

Moleküler Ağırlık

314,4000 g/mol

LogP

1,50

TPSA

98,40 Å²

Lipinski RO5

Geçer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

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SMILES

Nc1ccc(S(=O)(=O)Nc2ccnn2-c2ccccc2)cc1

InChI

InChI=1S/C15H14N4O2S/c16-12-6-8-14(9-7-12)22(20,21)18-15-10-11-17-19(15)13-4-2-1-3-5-13/h1-11,18H,16H2

Molecular Formula

C15H14N4O2S

HBD / HBA

2 / 5

Döndürülebilir Bağlar

4

Ağır Atomlar

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

Sulfaphenazole is a sulfonamide antibacterial and potent inhibitor of cytochrome P450 2C9 (CYP2C9), used primarily as a research tool to characterize CYP2C9-mediated drug metabolism, and historically as an antibacterial agent for urinary tract infections. Its CYP2C9 inhibition causes clinically significant interactions with drugs metabolized by this enzyme including warfarin, tolbutamide, and phenytoin. The antibacterial mechanism involves inhibition of dihydropteroate synthase.

Yes, Sulfaphenazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1109. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5335. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Formül: C15H14N4O2S

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.