SCN9A (Sodium Channel Nav1.7)

SCN9A

Voltage-gated sodium channel preferentially expressed in nociceptive neurons.

İşlev

Gain-of-function mutations cause inherited pain disorders. Blocking reduces pain signaling.

Bu Hedefe Etki Eden İlaçlar

İlaç Etki Birincil
Valproic Acid Blocker Evet
Topiramate Blocker Evet
Phenytoin Blocker Evet
Gabapentin Blocker Evet
Pregabalin Blocker Evet
Lamotrigine Blocker Evet
Carbamazepine Blocker Evet
Furosemide Inhibitor Evet
Hydrochlorothiazide Inhibitor Evet

Related Targets