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Albuterol

CHEMBL714 Phase 4 Đã phê duyệt Small molecule
Half-Life
3-8 hours
Bioavailability
—
Protein Binding
—
Molecular Weight
239.3 g/mol
LogP
0.3
Phase
4

A fast-acting bronchodilator that relaxes the muscles surrounding the airways in the lungs, allowing them to widen and making it easier to breathe during asthma attacks or other episodes of airway narrowing. It works within minutes of inhalation and is one of the most widely used rescue medications for acute breathing difficulties.

Khối lượng phân tử

239,3110 g/mol

LogP

0,30

TPSA

72,70 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Cardiovascular Disease Respiratory Disease Non-Small Cell Lung Cancer Rheumatoid Arthritis Asthma Chronic Obstructive Pulmonary Disease Multiple Sclerosis Stroke Deep Vein Thrombosis / Pulmonary Embolism Obesity Type 2 Diabetes Hypertension Major Depressive Disorder HIV/AIDS Tuberculosis Heart Failure Atrial Fibrillation

Phân loại thuốc

R — R - Respiratory System

Cơ chế tác dụng

Selective beta-2 adrenergic receptor agonist causing bronchodilation.

Pharmacokinetics (PK)

Half-Life 3-8 hours

Pharmacodynamics (PD)

Cơ chế

Selective beta-2 adrenergic receptor agonist causing bronchodilation.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC(C)(C)NCC(O)c1ccc(O)c(CO)c1

                

                

                
                

                    
InChI

                    
InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C13H21NO3

                    

                    
                    

                        
HBD / HBA

                        
4 / 4

                    

                    
                    

                        
Liên kết có thể quay

                        
5

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
17

                    

                    
                

            


            
            

                
                

                    
                    

                        

                            ADRB2 (Beta-2 Adrenergic Receptor)
                            Agonist
                        

                        
                        Primary Target
                        
                    

                    
                    

                        

                            ADRB1 (Beta-1 Adrenergic Receptor)
                            Agonist
                        

                        
                    

                    
                

                
            


            
            

                
                

                    
                    
                        

                            

  
  Major


                            
                                Albuterol + Propranolol
                            
                        

                        
                        
Propranolol, a non-selective beta-blocker, directly antagonises the bronchodilatory and cardiovascular effects of albuterol, potentially causing severe bronchospasm in patients with asthma or COPD.

                        
                    
                    
                    
                        

                            

  
  Moderate


                            
                                Albuterol + Digoxin
                            
                        

                        
                        
Albuterol-induced hypokalaemia can potentiate digoxin toxicity by increasing myocardial sensitivity to digoxin at any given plasma concentration.

                        
                    
                    
                

                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
A fast-acting bronchodilator that relaxes the muscles surrounding the airways in the lungs, allowing them to widen and making it easier to breathe during asthma attacks or other episodes of airway narrowing. It works within minutes of inhalation and is one of the most widely used rescue medications for acute breathing difficulties.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Selective beta-2 adrenergic receptor agonist causing bronchodilation.

                        

                    

                    

                    
                    

                        
                        

                            
Key pharmacokinetic parameters for Albuterol: Half-life: 3-8 hours.

                        

                    

                    

                    

                        
                        

                            
Yes, Albuterol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            
            

                
Related Drugs


                
                

                    
Same Drug Class

                    

                        
                        
                            Montelukast
                            Small molecule
                        
                        
                        
                            Cetirizine
                            Small molecule
                        
                        
                        
                            Loratadine
                            Small molecule
                        
                        
                        
                            Diphenhydramine
                            Small molecule
                        
                        
                    

                

                

                
                
                
            

            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL714.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2083.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.