Atenolol
A beta-1 selective adrenergic blocker that slows the heart rate and reduces the force of heart contractions, lowering blood pressure and decreasing the heart's oxygen demand. It is used for hypertension, angina, and heart rhythm disorders including atrial fibrillation.
Khối lượng phân tử
266,3360 g/mol
LogP
0,20
TPSA
84,60 Ų
Lipinski RO5
Đạt
Lĩnh vực điều trị
Phân loại thuốc
Cơ chế tác dụng
Cardioselective beta-1 adrenergic receptor blocker without intrinsic sympathomimetic activity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Cardioselective beta-1 adrenergic receptor blocker without intrinsic sympathomimetic activity.
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
CC(C)NCC(O)COc1ccc(CC(N)=O)cc1
InChI
InChI=1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
Molecular Formula
C14H22N2O3
HBD / HBA
3 / 4
Liên kết có thể quay
8
Nguyên tử nặng
19
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
A beta-1 selective adrenergic blocker that slows the heart rate and reduces the force of heart contractions, lowering blood pressure and decreasing the heart's oxygen demand. It is used for hypertension, angina, and heart rhythm disorders including atrial fibrillation.
Cardioselective beta-1 adrenergic receptor blocker without intrinsic sympathomimetic activity.
Key pharmacokinetic parameters for Atenolol: Half-life: 6-7 hours.
Yes, Atenolol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
Related Drugs
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL24. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2249. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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