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Diltiazem Malate

CHEMBL1200805 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
548.6 g/mol
LogP
—
Phase
4

A malate salt form of diltiazem, a calcium channel blocker used to treat high blood pressure, angina, and certain heart rhythm disorders. It works by relaxing blood vessels and slowing the heart rate.

Khối lượng phân tử

548,6000 g/mol

TPSA

179,00 Ų

Lĩnh vực điều trị

Cardiovascular Disease Pain Management Gastroesophageal Reflux Disease Stroke Deep Vein Thrombosis / Pulmonary Embolism Obesity Type 2 Diabetes Hypertension Chronic Pain Hepatitis C Heart Failure Atrial Fibrillation Colorectal Cancer

Cơ chế tác dụng

Benzothiazepine calcium channel blocker.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Benzothiazepine calcium channel blocker.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COc1ccc([C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O)cc1.O=C(O)CC(O)C(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C22H26N2O4S.C4H6O5/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3;5-2(4(8)9)1-3(6)7/h5-12,20-21H,13-14H2,1-4H3;2,5H,1H2,(H,6,7)(H,8,9)/t20-,21+;/m1./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C26H32N2O9S

                    

                    
                    

                        
HBD / HBA

                        
3 / 11

                    

                    
                    

                        
Liên kết có thể quay

                        
10

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
38

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
A malate salt form of diltiazem, a calcium channel blocker used to treat high blood pressure, angina, and certain heart rhythm disorders. It works by relaxing blood vessels and slowing the heart rate.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Benzothiazepine calcium channel blocker.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Diltiazem Malate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200805.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3037122.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.