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Lansoprazole

CHEMBL480 Phase 4 Đã phê duyệt Small molecule
Half-Life
1.5 hours
Bioavailability
—
Protein Binding
—
Molecular Weight
369.4 g/mol
LogP
2.8
Phase
4

A proton pump inhibitor (PPI) used to treat acid-related conditions including GERD, stomach ulcers, and Zollinger-Ellison syndrome. It works by irreversibly blocking the hydrogen-potassium ATPase enzyme in stomach cells to reduce acid production.

Khối lượng phân tử

369,3620 g/mol

LogP

2,80

TPSA

87,10 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Pain Management Non-Small Cell Lung Cancer Asthma Chronic Obstructive Pulmonary Disease Infectious Disease Gastroesophageal Reflux Disease Lymphoma Type 2 Diabetes Breast Cancer Gout Chronic Pain Colorectal Cancer

Phân loại thuốc

A — A - Alimentary Tract and Metabolism

Cơ chế tác dụng

Proton pump inhibitor.

Pharmacokinetics (PK)

Half-Life 1.5 hours

Pharmacodynamics (PD)

Cơ chế

Proton pump inhibitor.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
Cc1c(OCC(F)(F)F)ccnc1C[S+]([O-])c1nc2ccccc2[nH]1

                

                

                
                

                    
InChI

                    
InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H14F3N3O2S

                    

                    
                    

                        
HBD / HBA

                        
1 / 8

                    

                    
                    

                        
Liên kết có thể quay

                        
5

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
25

                    

                    
                

            


            
            

                
                

                    
                    

                        

                            ATP4A (Proton Pump (H+/K+-ATPase))
                            Inhibitor
                        

                        
                        Primary Target
                        
                    

                    
                

                
            


            
            

                
                

                    
                    
                        

                            

  
  Moderate


                            
                                Lansoprazole + Clopidogrel
                            
                        

                        
                        
Lansoprazole, like omeprazole, inhibits CYP2C19 and reduces clopidogrel's antiplatelet efficacy, potentially increasing cardiovascular event risk.

                        
                    
                    
                

                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
A proton pump inhibitor (PPI) used to treat acid-related conditions including GERD, stomach ulcers, and Zollinger-Ellison syndrome. It works by irreversibly blocking the hydrogen-potassium ATPase enzyme in stomach cells to reduce acid production.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Proton pump inhibitor.

                        

                    

                    

                    
                    

                        
                        

                            
Key pharmacokinetic parameters for Lansoprazole: Half-life: 1.5 hours.

                        

                    

                    

                    

                        
                        

                            
Yes, Lansoprazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            
            

                
Related Drugs


                
                

                    
Same Drug Class

                    

                        
                        
                            Metformin
                            Small molecule
                        
                        
                        
                            Omeprazole
                            Small molecule
                        
                        
                        
                            Pantoprazole
                            Small molecule
                        
                        
                        
                            Insulin Glargine
                            Protein
                        
                        
                    

                

                

                
                
                
            

            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL480.
                Open-access bioactivity database.
            
        
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  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3883.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.