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Menthol

CHEMBL256087 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
156.3 g/mol
LogP
3.0
Phase
4

This naturally occurring compound from peppermint and other mint plants creates a cooling sensation by activating cold-sensitive nerve receptors (TRPM8 channels) without actually changing temperature, making it widely used in topical pain relievers, cough drops, and skin care products. When applied to the skin or mucous membranes, it can temporarily relieve minor pain, itching, and congestion.

Khối lượng phân tử

156,2600 g/mol

LogP

3,00

TPSA

20,20 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Dermatology Pain Management Rheumatoid Arthritis Chronic Obstructive Pulmonary Disease Parkinson's Disease Migraine Schizophrenia Inflammatory Bowel Disease Stroke Obesity Type 2 Diabetes Hypertension Breast Cancer Atopic Dermatitis Gout Chronic Pain

Cơ chế tác dụng

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cơ chế

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC1CCC(C(C)C)C(O)C1

                

                

                
                

                    
InChI

                    
InChI=1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C10H20O

                    

                    
                    

                        
HBD / HBA

                        
1 / 1

                    

                    
                    

                        
Liên kết có thể quay

                        
1

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
11

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
This naturally occurring compound from peppermint and other mint plants creates a cooling sensation by activating cold-sensitive nerve receptors (TRPM8 channels) without actually changing temperature, making it widely used in topical pain relievers, cough drops, and skin care products. When applied to the skin or mucous membranes, it can temporarily relieve minor pain, itching, and congestion.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Menthol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL256087.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 1254.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.