Mezlocillin
This broad-spectrum acylureidopenicillin antibiotic was used to treat serious infections caused by gram-negative bacteria, including those affecting the abdomen, urinary tract, and blood. It has been largely replaced by other antibiotics with better stability and activity profiles.
Khối lượng phân tử
539,6000 g/mol
LogP
-0,20
TPSA
207,00 Ų
Lipinski RO5
Đạt
Lĩnh vực điều trị
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](NC(=O)N3CCN(S(C)(=O)=O)C3=O)c3ccccc3)C(=O)N2[C@H]1C(=O)O
InChI
InChI=1S/C21H25N5O8S2/c1-21(2)14(18(29)30)26-16(28)13(17(26)35-21)22-15(27)12(11-7-5-4-6-8-11)23-19(31)24-9-10-25(20(24)32)36(3,33)34/h4-8,12-14,17H,9-10H2,1-3H3,(H,22,27)(H,23,31)(H,29,30)/t12-,13-,14+,17-/m1/s1
Molecular Formula
C21H25N5O8S2
HBD / HBA
3 / 9
Liên kết có thể quay
6
Nguyên tử nặng
36
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
This broad-spectrum acylureidopenicillin antibiotic was used to treat serious infections caused by gram-negative bacteria, including those affecting the abdomen, urinary tract, and blood. It has been largely replaced by other antibiotics with better stability and activity profiles.
Yes, Mezlocillin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1731. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 656511. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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