Nalmefene Hydrochloride Dihydrate
A hydrochloride salt form of nalmefene with the same therapeutic properties. This medication is used to reduce alcohol consumption in adults who drink heavily, and it works by blocking opioid receptors in the brain that are involved in the rewarding effects of alcohol.
Khối lượng phân tử
411,9000 g/mol
TPSA
54,90 Ų
Cơ chế tác dụng
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
C=C1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5.Cl.O.O
InChI
InChI=1S/C21H25NO3.ClH.2H2O/c1-12-6-7-21(24)16-10-14-4-5-15(23)18-17(14)20(21,19(12)25-18)8-9-22(16)11-13-2-3-13;;;/h4-5,13,16,19,23-24H,1-3,6-11H2;1H;2*1H2/t16-,19+,20+,21-;;;/m1.../s1
Molecular Formula
C21H30ClNO5
HBD / HBA
5 / 6
Liên kết có thể quay
2
Nguyên tử nặng
28
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
A hydrochloride salt form of nalmefene with the same therapeutic properties. This medication is used to reduce alcohol consumption in adults who drink heavily, and it works by blocking opioid receptors in the brain that are involved in the rewarding effects of alcohol.
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.
Yes, Nalmefene Hydrochloride Dihydrate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL5315055. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 46209574. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="nalmefene-hydrochloride-dihydrate"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/nalmefene-hydrochloride-dihydrate/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/nalmefene-hydrochloride-dihydrate/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/nalmefene-hydrochloride-dihydrate/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="nalmefene-hydrochloride-dihydrate"></drugfyi-drug>