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Nebivolol

CHEMBL434394 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
405.4 g/mol
LogP
3.0
Phase
4

This highly selective beta-blocker is used to treat high blood pressure and heart failure by slowing the heart rate and reducing the force of heart contractions. It also has unique blood vessel-relaxing properties that help lower blood pressure further.

Khối lượng phân tử

405,4000 g/mol

LogP

3,00

TPSA

71,00 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Glaucoma Cardiovascular Disease Osteoporosis Chronic Obstructive Pulmonary Disease Chronic Kidney Disease Stroke Lymphoma Type 2 Diabetes Hypertension Breast Cancer Heart Failure Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
OC(CNCC(O)C1CCc2cc(F)ccc2O1)C1CCc2cc(F)ccc2O1

                

                

                
                

                    
InChI

                    
InChI=1S/C22H25F2NO4/c23-15-3-7-19-13(9-15)1-5-21(28-19)17(26)11-25-12-18(27)22-6-2-14-10-16(24)4-8-20(14)29-22/h3-4,7-10,17-18,21-22,25-27H,1-2,5-6,11-12H2

                

                

                

                    
                    

                        
Molecular Formula

                        
C22H25F2NO4

                    

                    
                    

                        
HBD / HBA

                        
3 / 7

                    

                    
                    

                        
Liên kết có thể quay

                        
6

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
29

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
This highly selective beta-blocker is used to treat high blood pressure and heart failure by slowing the heart rate and reducing the force of heart contractions. It also has unique blood vessel-relaxing properties that help lower blood pressure further.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Nebivolol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL434394.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 71301.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.