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Penicillin V

CHEMBL615 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
350.4 g/mol
LogP
2.1
Phase
4

Acid stability is what allows penicillin V to be given by mouth where benzylpenicillin cannot, and that property defines its clinical niche. The agent treats mild to moderate bacterial infections, streptococcal pharyngitis and skin infections among them, acting through the beta-lactam mechanism common to the class: interference with the cross-linking of peptidoglycan leaves the bacterial cell wall unable to withstand internal osmotic pressure. Its spectrum is narrower than that of the aminopenicillins and it offers no protection against beta-lactamase-producing staphylococci. The compound is a small molecule with formula C16H18N2O5S and a molecular weight of approximately 350.4 g/mol. It is approved and has completed the final phase of clinical development.

This oral penicillin antibiotic treats mild to moderate bacterial infections such as strep throat and skin infections.

Khối lượng phân tử

350,4000 g/mol

LogP

2,10

TPSA

121,00 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Infectious Disease

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C16H18N2O5S/c1-16(2)12(15(21)22)18-13(20)11(14(18)24-16)17-10(19)8-23-9-6-4-3-5-7-9/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/t11-,12+,14-/m1/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H18N2O5S

                    

                    
                    

                        
HBD / HBA

                        
2 / 6

                    

                    
                    

                        
Liên kết có thể quay

                        
5

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
24

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
This oral penicillin antibiotic treats mild to moderate bacterial infections such as strep throat and skin infections.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Penicillin V is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL615.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 6869.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-08-20.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.