Propyliodone
Propyliodone is an iodinated oil contrast medium formerly used for bronchography to delineate the bronchial tree radiographically by filling the airways with a radiopaque iodine-containing compound. It has largely been replaced by modern CT bronchography and other imaging modalities, but was valuable for the diagnosis of bronchial and pulmonary diseases in the mid-20th century.
Khối lượng phân tử
447,0100 g/mol
LogP
2,40
TPSA
46,60 Ų
Lipinski RO5
Đạt
Cơ chế tác dụng
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
CCCOC(=O)Cn1cc(I)c(=O)c(I)c1
InChI
InChI=1S/C10H11I2NO3/c1-2-3-16-9(14)6-13-4-7(11)10(15)8(12)5-13/h4-5H,2-3,6H2,1H3
Molecular Formula
C10H11I2NO3
HBD / HBA
- / 4
Liên kết có thể quay
5
Nguyên tử nặng
16
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
Propyliodone is an iodinated oil contrast medium formerly used for bronchography to delineate the bronchial tree radiographically by filling the airways with a radiopaque iodine-containing compound. It has largely been replaced by modern CT bronchography and other imaging modalities, but was valuable for the diagnosis of bronchial and pulmonary diseases in the mid-20th century.
Enhances the contrast of specific tissues or structures during medical imaging procedures by altering the local signal intensity or X-ray absorption characteristics.
Yes, Propyliodone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200821. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4949. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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