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Rabeprazole

CHEMBL1219 Phase 4 Đã phê duyệt Small molecule
Half-Life
1-2 hours
Bioavailability
—
Protein Binding
—
Molecular Weight
359.4 g/mol
LogP
1.9
Phase
4

A proton pump inhibitor that reduces stomach acid production, used to treat gastroesophageal reflux disease, stomach ulcers, and related conditions. It provides relief from heartburn and helps the esophagus heal from acid damage.

Khối lượng phân tử

359,4440 g/mol

LogP

1,90

TPSA

96,30 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Asthma Insomnia Infectious Disease Gastroesophageal Reflux Disease Non-Alcoholic Fatty Liver Disease Lymphoma Breast Cancer Atrial Fibrillation Prostate Cancer Colorectal Cancer

Phân loại thuốc

A — A - Alimentary Tract and Metabolism

Cơ chế tác dụng

Proton pump inhibitor irreversibly inhibiting gastric H+/K+-ATPase with faster onset than omeprazole.

Pharmacokinetics (PK)

Half-Life 1-2 hours

Pharmacodynamics (PD)

Cơ chế

Proton pump inhibitor irreversibly inhibiting gastric H+/K+-ATPase with faster onset than omeprazole.

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
COCCCOc1ccnc(C[S+]([O-])c2nc3ccccc3[nH]2)c1C

                

                

                
                

                    
InChI

                    
InChI=1S/C18H21N3O3S/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18/h3-4,6-9H,5,10-12H2,1-2H3,(H,20,21)

                

                

                

                    
                    

                        
Molecular Formula

                        
C18H21N3O3S

                    

                    
                    

                        
HBD / HBA

                        
1 / 6

                    

                    
                    

                        
Liên kết có thể quay

                        
8

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
25

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
A proton pump inhibitor that reduces stomach acid production, used to treat gastroesophageal reflux disease, stomach ulcers, and related conditions. It provides relief from heartburn and helps the esophagus heal from acid damage.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Proton pump inhibitor irreversibly inhibiting gastric H+/K+-ATPase with faster onset than omeprazole.

                        

                    

                    

                    
                    

                        
                        

                            
Key pharmacokinetic parameters for Rabeprazole: Half-life: 1-2 hours.

                        

                    

                    

                    

                        
                        

                            
Yes, Rabeprazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            
            

                
Related Drugs


                
                

                    
Same Drug Class

                    

                        
                        
                            Metformin
                            Small molecule
                        
                        
                        
                            Omeprazole
                            Small molecule
                        
                        
                        
                            Pantoprazole
                            Small molecule
                        
                        
                        
                            Lansoprazole
                            Small molecule
                        
                        
                    

                

                

                
            

            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1219.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5029.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.