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Sufentanil

CHEMBL658 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
386.6 g/mol
LogP
4.0
Phase
4

A potent synthetic opioid approximately 5 to 10 times stronger than fentanyl, used in carefully controlled anesthetic and intensive care settings to provide powerful pain relief and sedation. A sublingual microtablet formulation has also been developed for managing moderate to severe acute pain in supervised healthcare settings.

Khối lượng phân tử

386,6000 g/mol

LogP

4,00

TPSA

61,00 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Cardiovascular Disease Pain Management Non-Small Cell Lung Cancer Parkinson's Disease Generalized Anxiety Disorder Melanoma Oncology Inflammatory Bowel Disease Chronic Kidney Disease Stroke Obesity Hypertension Breast Cancer Chronic Pain Atrial Fibrillation Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CCC(=O)N(c1ccccc1)C1(COC)CCN(CCc2cccs2)CC1

                

                

                
                

                    
InChI

                    
InChI=1S/C22H30N2O2S/c1-3-21(25)24(19-8-5-4-6-9-19)22(18-26-2)12-15-23(16-13-22)14-11-20-10-7-17-27-20/h4-10,17H,3,11-16,18H2,1-2H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C22H30N2O2S

                    

                    
                    

                        
HBD / HBA

                        
- / 4

                    

                    
                    

                        
Liên kết có thể quay

                        
8

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
27

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
A potent synthetic opioid approximately 5 to 10 times stronger than fentanyl, used in carefully controlled anesthetic and intensive care settings to provide powerful pain relief and sedation. A sublingual microtablet formulation has also been developed for managing moderate to severe acute pain in supervised healthcare settings.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Sufentanil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL658.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 41693.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.