Trientine Hydrochloride
Trientine hydrochloride is the hydrochloride salt form of trientine, a copper-chelating agent used for Wilson's disease and under investigation as an anti-fibrotic agent in melanoma through copper-dependent pathways. See trientine for complete pharmacological details. This salt formulation is used in approved oral capsule preparations.
Khối lượng phân tử
219,1500 g/mol
TPSA
76,10 Ų
Lĩnh vực điều trị
Cơ chế tác dụng
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
Cl.Cl.NCCNCCNCCN
InChI
InChI=1S/C6H18N4.2ClH/c7-1-3-9-5-6-10-4-2-8;;/h9-10H,1-8H2;2*1H
Molecular Formula
C6H20Cl2N4
HBD / HBA
6 / 4
Liên kết có thể quay
7
Nguyên tử nặng
12
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
Trientine hydrochloride is the hydrochloride salt form of trientine, a copper-chelating agent used for Wilson's disease and under investigation as an anti-fibrotic agent in melanoma through copper-dependent pathways. See trientine for complete pharmacological details. This salt formulation is used in approved oral capsule preparations.
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Yes, Trientine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989777. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 71433. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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