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Vilanterol

CHEMBL1198857 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
486.4 g/mol
LogP
3.8
Phase
4

Vilanterol is a long-acting beta-2 adrenergic agonist (LABA) with ultra-long duration of action (>24 hours) that activates beta-2 receptors in bronchial smooth muscle, producing sustained bronchodilation through cAMP-mediated relaxation. It is used exclusively in combination with inhaled corticosteroids (fluticasone furoate) or as a dual bronchodilator (with umeclidinium) for maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD). Its 24-hour duration enables once-daily dosing.

Khối lượng phân tử

486,4000 g/mol

LogP

3,80

TPSA

91,20 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Respiratory Disease Asthma Chronic Obstructive Pulmonary Disease Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
OCc1cc([C@@H](O)CNCCCCCCOCCOCc2c(Cl)cccc2Cl)ccc1O

                

                

                
                

                    
InChI

                    
InChI=1S/C24H33Cl2NO5/c25-21-6-5-7-22(26)20(21)17-32-13-12-31-11-4-2-1-3-10-27-15-24(30)18-8-9-23(29)19(14-18)16-28/h5-9,14,24,27-30H,1-4,10-13,15-17H2/t24-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C24H33Cl2NO5

                    

                    
                    

                        
HBD / HBA

                        
4 / 6

                    

                    
                    

                        
Liên kết có thể quay

                        
16

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
32

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
Vilanterol is a long-acting beta-2 adrenergic agonist (LABA) with ultra-long duration of action (>24 hours) that activates beta-2 receptors in bronchial smooth muscle, producing sustained bronchodilation through cAMP-mediated relaxation. It is used exclusively in combination with inhaled corticosteroids (fluticasone furoate) or as a dual bronchodilator (with umeclidinium) for maintenance treatment of asthma and chronic obstructive pulmonary disease (COPD). Its 24-hour duration enables once-daily dosing.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Vilanterol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1198857.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 10184665.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.