Chirality
The property of a molecule that is non-superimposable on its mirror image. Enantiomers can have dramatically different pharmacological activity, potency, and toxicity profiles.
Ví dụ
- S-omeprazole (esomeprazole)
- R/S-warfarin (different potency)
- Thalidomide (R-sedative, S-teratogenic)
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The property of a molecule that is non-superimposable on its mirror image. Enantiomers can have dramatically different pharmacological activity, potency, and toxicity profiles.