Number Needed to Harm (NNH)

NNH

Clinical

The number of patients exposed to a drug for one additional patient to experience an adverse event compared to control. Calculated as 1/absolute risk increase (ARI). Higher NNH indicates better safety.

Ví dụ

Comparing NNT/NNH for risk-benefit
NNH for GI bleeding with NSAIDs
Ideal NNH = infinity

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The number of patients exposed to a drug for one additional patient to experience an adverse event compared to control. Calculated as 1/absolute risk increase (ARI). Higher NNH indicates better …