Acetylcysteine
A medication that replenishes glutathione, a key antioxidant in the body, and is used as the primary antidote for acetaminophen overdose to prevent liver failure. It also thins and loosens thick mucus in the airways, making it useful in conditions such as cystic fibrosis, chronic bronchitis, and to clear mucus before respiratory procedures. When given intravenously for overdose, it is most effective when started within eight hours of ingestion.
分子量
163.2000 g/mol
LogP
0.40
TPSA
67.40 Ų
Lipinski 五规则
符合
治疗领域
作用机制
Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.
二维结构
Cite this structure
Embed this structure
SMILES
CC(=O)N[C@@H](CS)C(=O)O
InChI
InChI=1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
Molecular Formula
C5H9NO3S
HBD / HBA
3 / 4
可旋转键数
3
重原子数
10
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
A medication that replenishes glutathione, a key antioxidant in the body, and is used as the primary antidote for acetaminophen overdose to prevent liver failure. It also thins and loosens thick mucus in the airways, making it useful in conditions such as cystic fibrosis, chronic bronchitis, and to clear mucus before respiratory procedures. When given intravenously for overdose, it is most effective when started within eight hours of ingestion.
Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.
Yes, Acetylcysteine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL600. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 12035. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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