Acetylcysteine

CHEMBL600 Phase 4 Aprovado Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
163.2 g/mol
LogP
0.4
Phase
4

A medication that replenishes glutathione, a key antioxidant in the body, and is used as the primary antidote for acetaminophen overdose to prevent liver failure. It also thins and loosens thick mucus in the airways, making it useful in conditions such as cystic fibrosis, chronic bronchitis, and to clear mucus before respiratory procedures. When given intravenously for overdose, it is most effective when started within eight hours of ingestion.

Peso Molecular

163,2000 g/mol

LogP

0,40

TPSA

67,40 Ų

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Mecanismo de Ação

Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mecanismo

Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.

Estrutura 2D

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SMILES

CC(=O)N[C@@H](CS)C(=O)O

InChI

InChI=1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1

Molecular Formula

C5H9NO3S

HBD / HBA

3 / 4

Ligações Rotacionáveis

3

Átomos Pesados

10

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

A medication that replenishes glutathione, a key antioxidant in the body, and is used as the primary antidote for acetaminophen overdose to prevent liver failure. It also thins and loosens thick mucus in the airways, making it useful in conditions such as cystic fibrosis, chronic bronchitis, and to clear mucus before respiratory procedures. When given intravenously for overdose, it is most effective when started within eight hours of ingestion.

Counteracts the effects of a specific toxin or drug overdose through competitive antagonism, enhanced elimination, or direct chemical neutralization.

Yes, Acetylcysteine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL600. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 12035. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.