Bazedoxifene

CHEMBL46740 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

470.6 g/mol

LogP

6.1

Phase

4

A selective estrogen receptor modulator that acts as an estrogen antagonist in breast and uterine tissue while providing estrogen-like protection to bone, used to prevent postmenopausal osteoporosis.

分子量

470.6000 g/mol

LogP

6.10

TPSA

57.90 Å²

Lipinski 五规则

符合

治疗领域

Endometriosis Osteoporosis Schizophrenia Generalized Anxiety Disorder Multiple Sclerosis Obesity Breast Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

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SMILES

Cc1c(-c2ccc(O)cc2)n(Cc2ccc(OCCN3CCCCCC3)cc2)c2ccc(O)cc12

InChI

InChI=1S/C30H34N2O3/c1-22-28-20-26(34)12-15-29(28)32(30(22)24-8-10-25(33)11-9-24)21-23-6-13-27(14-7-23)35-19-18-31-16-4-2-3-5-17-31/h6-15,20,33-34H,2-5,16-19,21H2,1H3

Molecular Formula

C30H34N2O3

HBD / HBA

2 / 4

可旋转键数

7

重原子数

35

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

A selective estrogen receptor modulator that acts as an estrogen antagonist in breast and uterine tissue while providing estrogen-like protection to bone, used to prevent postmenopausal osteoporosis.

Yes, Bazedoxifene is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL46740. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 154257. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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结构

快速数据

分子式: C30H34N2O3

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.