Bromfenac

CHEMBL1077 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

334.2 g/mol

LogP

3.3

Phase

4

A nonsteroidal anti-inflammatory drug formulated as eye drops to reduce pain and inflammation following cataract surgery. It works by inhibiting cyclooxygenase enzymes in the eye to block prostaglandin production. Its twice-daily or once-daily dosing schedule improves convenience for patients recovering from eye surgery.

分子量

334.1600 g/mol

LogP

3.30

TPSA

80.40 Å²

Lipinski 五规则

符合

治疗领域

Glaucoma Age-Related Macular Degeneration Pain Management Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

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SMILES

Nc1c(CC(=O)O)cccc1C(=O)c1ccc(Br)cc1

InChI

InChI=1S/C15H12BrNO3/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19/h1-7H,8,17H2,(H,18,19)

Molecular Formula

C15H12BrNO3

HBD / HBA

2 / 4

可旋转键数

4

重原子数

20

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

A nonsteroidal anti-inflammatory drug formulated as eye drops to reduce pain and inflammation following cataract surgery. It works by inhibiting cyclooxygenase enzymes in the eye to block prostaglandin production. Its twice-daily or once-daily dosing schedule improves convenience for patients recovering from eye surgery.

Yes, Bromfenac is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1077. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 60726. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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结构

快速数据

分子式: C15H12BrNO3
同义词: 9

外部链接

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.