Clobutinol

CHEMBL1474889 Phase 4 已批准 Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
255.8 g/mol
LogP
3.2
Phase
4

An antitussive medication that was used to suppress coughs by acting on the cough center in the brain. It was once available over the counter in several countries but was withdrawn from markets due to concerns about serious heart rhythm disturbances. It should no longer be used.

分子量

255.7800 g/mol

LogP

3.20

TPSA

23.50 Ų

Lipinski 五规则

符合

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

SVG PNG

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SMILES

CC(CN(C)C)C(C)(O)Cc1ccc(Cl)cc1

InChI

InChI=1S/C14H22ClNO/c1-11(10-16(3)4)14(2,17)9-12-5-7-13(15)8-6-12/h5-8,11,17H,9-10H2,1-4H3

Molecular Formula

C14H22ClNO

HBD / HBA

1 / 2

可旋转键数

5

重原子数

17

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

An antitussive medication that was used to suppress coughs by acting on the cough center in the brain. It was once available over the counter in several countries but was withdrawn from markets due to concerns about serious heart rhythm disturbances. It should no longer be used.

Yes, Clobutinol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1474889. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 26937. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.