Pentetate Indium Disodium In 111
A radioactive imaging agent in which indium-111 is chelated by DTPA, used in nuclear medicine to image cerebrospinal fluid spaces (cisternography) and evaluate CSF leaks or hydrocephalus. It is instilled intrathecally and its distribution is tracked by gamma camera imaging.
分子量
545.1900 g/mol
TPSA
210.00 Ų
作用机制
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
SMILES
C(CN(CC(=O)[O-])CC(=O)[O-])N(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[111In+3]
InChI
InChI=1S/C14H23N3O10.In.2Na/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;;;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);;;/q;+3;2*+1/p-5/i;1-4;;
Molecular Formula
C14H18InN3Na2O10
HBD / HBA
- / 13
可旋转键数
11
重原子数
30
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
常见问题
A radioactive imaging agent in which indium-111 is chelated by DTPA, used in nuclear medicine to image cerebrospinal fluid spaces (cisternography) and evaluate CSF leaks or hydrocephalus. It is instilled intrathecally and its distribution is tracked by gamma camera imaging.
Forms stable, water-soluble chelate complexes with specific metal ions, facilitating their excretion from the body through the kidneys. This reduces toxic metal burden in affected tissues.
Yes, Pentetate Indium Disodium In 111 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2107480. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 23724985. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="pentetate-indium-disodium-in-111"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/pentetate-indium-disodium-in-111/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/pentetate-indium-disodium-in-111/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/pentetate-indium-disodium-in-111/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="pentetate-indium-disodium-in-111"></drugfyi-drug>