Toremifene

CHEMBL1655 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

406.0 g/mol

LogP

7.2

Phase

4

This selective estrogen receptor modulator (SERM) is used to treat metastatic breast cancer in postmenopausal women whose tumors are estrogen receptor-positive. Like tamoxifen, it works by competing with estrogen to bind to its receptors in breast cancer cells, slowing their growth. It may slightly increase the risk of uterine cancer and blood clots with long-term use.

分子量

406.0000 g/mol

LogP

7.20

TPSA

12.50 Å²

Lipinski 五规则

符合

治疗领域

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Osteoporosis Breast Cancer Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

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SMILES

CN(C)CCOc1ccc(/C(=C(/CCCl)c2ccccc2)c2ccccc2)cc1

InChI

InChI=1S/C26H28ClNO/c1-28(2)19-20-29-24-15-13-23(14-16-24)26(22-11-7-4-8-12-22)25(17-18-27)21-9-5-3-6-10-21/h3-16H,17-20H2,1-2H3/b26-25-

Molecular Formula

C26H28ClNO

HBD / HBA

- / 2

可旋转键数

9

重原子数

29

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

This selective estrogen receptor modulator (SERM) is used to treat metastatic breast cancer in postmenopausal women whose tumors are estrogen receptor-positive. Like tamoxifen, it works by competing with estrogen to bind to its receptors in breast cancer cells, slowing their growth. It may slightly increase the risk of uterine cancer and blood clots with long-term use.

Yes, Toremifene is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1655. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3005573. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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结构

快速数据

分子式: C26H28ClNO
同义词: 1

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.