Phenacemide

CHEMBL918 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
178.2 g/mol
LogP
0.9
Phase
4

Phenacemide is an anticonvulsant agent of the acylureide class that was historically used in the management of severe, refractory epilepsy, particularly complex partial seizures. Its mechanism involves stabilization of neuronal membranes, though its significant hepatotoxic and psychiatric side effects have led to its discontinuation in most markets.

Molekularmasse

178,1900 g/mol

LogP

0,90

TPSA

72,20 Ų

Lipinski-Regel der Fünf

Bestanden

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure


                        

Embed this structure


                        

SMILES

NC(=O)NC(=O)Cc1ccccc1

InChI

InChI=1S/C9H10N2O2/c10-9(13)11-8(12)6-7-4-2-1-3-5-7/h1-5H,6H2,(H3,10,11,12,13)

Molecular Formula

C9H10N2O2

HBD / HBA

2 / 2

Rotierbare Bindungen

2

Schwere Atome

13

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Phenacemide is an anticonvulsant agent of the acylureide class that was historically used in the management of severe, refractory epilepsy, particularly complex partial seizures. Its mechanism involves stabilization of neuronal membranes, though its significant hepatotoxic and psychiatric side effects have led to its discontinuation in most markets.

Yes, Phenacemide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL918. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 4753. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.