Sodium Iodide I 131
Sodium iodide I-131 is a beta and gamma-emitting radioactive iodine used therapeutically for ablation of normal thyroid remnants post-thyroidectomy, treatment of differentiated thyroid cancer metastases, and hyperthyroidism, as well as diagnostically for thyroid cancer staging. The thyroid's avid uptake of iodide concentrates the radioactive iodine-131, where beta emissions deliver targeted radiation to destroy thyroid tissue. It is a cornerstone of differentiated thyroid cancer management following surgery.
Masse moléculaire
153,8959 g/mol
TPSA
0,00 Ų
Aires thérapeutiques
Mécanisme d'action
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
Structure 2D
Cite this structure
Embed this structure
SMILES
[131I-].[Na+]
InChI
InChI=1S/HI.Na/h1H;/q;+1/p-1/i1+4;
Molecular Formula
INa
HBD / HBA
- / 1
Liaisons Rotatives
0
Atomes Lourds
2
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Foire aux questions
Sodium iodide I-131 is a beta and gamma-emitting radioactive iodine used therapeutically for ablation of normal thyroid remnants post-thyroidectomy, treatment of differentiated thyroid cancer metastases, and hyperthyroidism, as well as diagnostically for thyroid cancer staging. The thyroid's avid uptake of iodide concentrates the radioactive iodine-131, where beta emissions deliver targeted radiation to destroy thyroid tissue. It is a cornerstone of differentiated thyroid cancer management following surgery.
Functions as a diagnostic agent by providing contrast enhancement or radioactive tracer activity that enables visualization of anatomical structures or physiological processes during medical imaging.
Yes, Sodium Iodide I 131 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201084. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 71368. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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