Allopurinol
A xanthine oxidase inhibitor that reduces the production of uric acid in the body, used primarily to prevent gout attacks and kidney stones caused by uric acid crystal buildup in joints and the urinary tract. It is also used to prevent elevated uric acid levels during cancer treatment when chemotherapy causes rapid breakdown of cancer cells.
आणविक भार
136.1120 g/mol
LogP
-0.70
TPSA
70.10 Ų
लिपिंस्की RO5
उत्तीर्ण
चिकित्सीय क्षेत्र
दवा वर्ग
क्रिया का तंत्र
Xanthine oxidase inhibitor reducing uric acid production.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Xanthine oxidase inhibitor reducing uric acid production.
2D संरचना
Cite this structure
Embed this structure
SMILES
Oc1ncnc2[nH]ncc12
InChI
InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
Molecular Formula
C5H4N4O
HBD / HBA
2 / 3
घूर्णनीय बंधन
0
भारी परमाणु
10
The combination of allopurinol and amoxicillin is associated with a markedly increased incidence of skin rashes (primarily maculopapular), though the rash is usually non-severe and reversible.
Low-dose aspirin reduces the uricosuric effect of allopurinol and may increase uric acid levels, potentially triggering gout flares.
No side effects recorded
Side effect data is not yet available for this drug.
अक्सर पूछे जाने वाले प्रश्न
A xanthine oxidase inhibitor that reduces the production of uric acid in the body, used primarily to prevent gout attacks and kidney stones caused by uric acid crystal buildup in joints and the urinary tract. It is also used to prevent elevated uric acid levels during cancer treatment when chemotherapy causes rapid breakdown of cancer cells.
Xanthine oxidase inhibitor reducing uric acid production.
Key pharmacokinetic parameters for Allopurinol: Half-life: 1-2 hours.
Yes, Allopurinol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
Related Drugs
Same Drug Class
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1467. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 135401907. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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