PTGS2 (Cyclooxygenase-2)
PTGS2
Inducible cyclooxygenase isoform upregulated during inflammation and pain signaling.
機能
Catalyzes prostaglandin H2 synthesis at sites of inflammation. Primary target of NSAIDs and selective COX-2 inhibitors (coxibs).
この標的に作用する薬物
| 薬物 | 作用 | 主要 |
|---|---|---|
| Montelukast | Antagonist | はい |
| Naproxen | Inhibitor | はい |
| Celecoxib | Inhibitor | はい |
| Ibuprofen | Inhibitor | はい |
| Doxycycline | Inhibitor | はい |
| Hydroxychloroquine | Inhibitor | はい |
| Allopurinol | Inhibitor | はい |
| Acetaminophen | Inhibitor | はい |
| Aspirin | Inhibitor | — |
| Prednisone | Inhibitor | — |
| Dexamethasone | Inhibitor | — |
| Methotrexate | Inhibitor | — |