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Propylthiouracil

CHEMBL1518 Phase 4 승인됨 Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
170.2 g/mol
LogP
0.8
Phase
4

Used to treat an overactive thyroid gland (hyperthyroidism) by blocking the production of thyroid hormones, and is sometimes used before thyroid surgery or radioactive iodine treatment. It requires regular monitoring of blood counts and liver function due to rare but serious risks of low white blood cell counts and liver damage.

분자량

170.2300 g/mol

LogP

0.80

TPSA

73.20 Ų

리핀스키 5의 법칙

통과

치료 영역

Non-Small Cell Lung Cancer Stroke Breast Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D 구조

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CCCc1cc(=O)[nH]c(=S)[nH]1

                

                

                
                

                    
InChI

                    
InChI=1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)

                

                

                

                    
                    

                        
Molecular Formula

                        
C7H10N2OS

                    

                    
                    

                        
HBD / HBA

                        
2 / 2

                    

                    
                    

                        
회전 가능 결합

                        
2

                    

                    
                    
                    

                        
무거운 원자

                        
11

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
자주 묻는 질문

                

                    
                    

                        
                        

                            
Used to treat an overactive thyroid gland (hyperthyroidism) by blocking the production of thyroid hormones, and is sometimes used before thyroid surgery or radioactive iodine treatment. It requires regular monitoring of blood counts and liver function due to rare but serious risks of low white blood cell counts and liver damage.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Propylthiouracil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1518.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 657298.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
의학적 면책조항

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.