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Propylthiouracil

CHEMBL1518 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
170.2 g/mol
LogP
0.8
Phase
4

Used to treat an overactive thyroid gland (hyperthyroidism) by blocking the production of thyroid hormones, and is sometimes used before thyroid surgery or radioactive iodine treatment. It requires regular monitoring of blood counts and liver function due to rare but serious risks of low white blood cell counts and liver damage.

Khối lượng phân tử

170,2300 g/mol

LogP

0,80

TPSA

73,20 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Non-Small Cell Lung Cancer Stroke Breast Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CCCc1cc(=O)[nH]c(=S)[nH]1

                

                

                
                

                    
InChI

                    
InChI=1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)

                

                

                

                    
                    

                        
Molecular Formula

                        
C7H10N2OS

                    

                    
                    

                        
HBD / HBA

                        
2 / 2

                    

                    
                    

                        
Liên kết có thể quay

                        
2

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
11

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
Used to treat an overactive thyroid gland (hyperthyroidism) by blocking the production of thyroid hormones, and is sometimes used before thyroid surgery or radioactive iodine treatment. It requires regular monitoring of blood counts and liver function due to rare but serious risks of low white blood cell counts and liver damage.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Propylthiouracil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1518.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 657298.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.